Journal of Cancer Research and Therapeutics Close
 

Figure 4: Applications of OncoDynamiX in drug discovery and development in oncology. The figure illustrates how OncoDynamiX can assist in selection of appropriate cancer cell lines and biomarkers in anti-cancer drug development in Glioblastoma. 1-5: Selection of glioblastoma cell lines representing alterations in pharmacological pathway, corresponding biomarkers, phenotypic endpoints integrated with multi-omics, 6: Prediction of response scores in cell lines and in patients, 7: Experimental verification of predictions, 8: Stratification of response of cell lines and patients to drug using multi-omics data, 9: Stratification of patients into responders and non-responders that enables selection of patients for showing successful treatment. REPHRASE??

Figure 4: Applications of OncoDynamiX in drug discovery and development in oncology. The figure illustrates how OncoDynamiX can assist in selection of appropriate cancer cell lines and biomarkers in anti-cancer drug development in Glioblastoma. 1-5: Selection of glioblastoma cell lines representing alterations in pharmacological pathway, corresponding biomarkers, phenotypic endpoints integrated with multi-omics, 6: Prediction of response scores in cell lines and in patients, 7: Experimental verification of predictions, 8: Stratification of response of cell lines and patients to drug using multi-omics data, 9: Stratification of patients into responders and non-responders that enables selection of patients for showing successful treatment. REPHRASE??