Journal of Cancer Research and Therapeutics Close
 

Figure 5: Selenocystine attenuates the growth of choriocarcinoma tumor xenografts in vivo. Selenocystine inhibits tumor volume (a) and tumor weight (b). JEG-3 cells (107 cells) were injected subcutaneously in nude mice. After growing for 1 week, the mice were administrated selenocystine at 5 and 10 mg/kg. The tumor volume and weight were measured at the end of the experiment. (c) Selenocystine induced apoptosis and oxidative damage in vivo. The protein expression was assayed by western blotting. (d) Selenocystine abolished the cell proliferation and angiogenesis in vivo. The Ki-67 and CD-31 expressions in vivo were examined with immunohistochemical method

Figure 5: Selenocystine attenuates the growth of choriocarcinoma tumor xenografts <i>in vivo</i>. Selenocystine inhibits tumor volume (a) and tumor weight (b). JEG-3 cells (10<sup>7</sup> cells) were injected subcutaneously in nude mice. After growing for 1 week, the mice were administrated selenocystine at 5 and 10 mg/kg. The tumor volume and weight were measured at the end of the experiment. (c) Selenocystine induced apoptosis and oxidative damage <i>in vivo.</i> The protein expression was assayed by western blotting. (d) Selenocystine abolished the cell proliferation and angiogenesis <i>in vivo</i>. The Ki-67 and CD-31 expressions <i>in vivo</i> were examined with immunohistochemical method