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Figure 3: Immunohistochemical features of extranodal natural-killer/T-cell lymphoma, nasal type: Neoplastic lymphoid cells expressing LCA (a), CD56 with membranous immunoreactivity (b), cytoplasmic CD3 expression (c). Immunoreactivity for cytotoxic molecule-granzyme-B (d). Neoplastic cells showing high proliferation with Ki67 (e) (immunoperoxidase stain, HRP polymer method). Neoplastic cells showing nuclear positivity for Epstein–Barr virus encoded RNA in situ hybridization (rapid in situ hybridization by digoxin-antidigoxin method) (f)

Figure 3: Immunohistochemical features of extranodal natural-killer/T-cell lymphoma, nasal type: Neoplastic lymphoid cells expressing LCA (a), CD56 with membranous immunoreactivity (b), cytoplasmic CD3 expression (c). Immunoreactivity for cytotoxic molecule-granzyme-B (d). Neoplastic cells showing high proliferation with Ki67 (e) (immunoperoxidase stain, HRP polymer method). Neoplastic cells showing nuclear positivity for Epstein–Barr virus encoded RNA <i>in situ</i> hybridization (rapid <i>in situ</i> hybridization by digoxin-antidigoxin method) (f)