Journal of Cancer Research and Therapeutics

REVIEW ARTICLE
Year
: 2021  |  Volume : 17  |  Issue : 6  |  Page : 1307--1313

Primary gastrointestinal anaplastic large cell lymphoma: A critical reappraisal with a systematic review of the world literature


Pritinanda Mishra1, Susama Patra1, Anand Srinivasan2, Somanath Padhi1, Mukund Namdev Sable1, Subash Chandra Samal3, Sonali Mohapatra4 
1 Deprtment of Pathology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
2 Deprtment of Pharmacology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
3 Deprtment of Gastroenterology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
4 Deprtment of Medical Oncology/Hematology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India

Correspondence Address:
Sonali Mohapatra
Department of Medical Oncology, All India Institute of Medical Sciences, Bhubaneswar, Odisha
India

Anaplastic large cell lymphoma (ALCL) is a distinct T-cell non-Hodgkin lymphoma involving both nodal and extra-nodal sites with a specific anaplastic lymphoma kinase 1 (ALK-1) gene rearrangement. The commonly involved extranodal sites include skin, bone, soft tissue, lungs, and liver. ALCL primarily involving gastrointestinal (GI) tract is rare. In this manuscript, we describe a case of primary esophageal ALK1 positive-ALCL (null phenotype) in a young female, who presented with fleshy mucosal lesion in the lower third of the esophagus and present a systematic review of 35 cases of GI-ALCL reported in the English literature over the past 28 years (1990–2018) with regard to the clinicopathological characteristics, therapy, and outcome.


How to cite this article:
Mishra P, Patra S, Srinivasan A, Padhi S, Sable MN, Samal SC, Mohapatra S. Primary gastrointestinal anaplastic large cell lymphoma: A critical reappraisal with a systematic review of the world literature.J Can Res Ther 2021;17:1307-1313


How to cite this URL:
Mishra P, Patra S, Srinivasan A, Padhi S, Sable MN, Samal SC, Mohapatra S. Primary gastrointestinal anaplastic large cell lymphoma: A critical reappraisal with a systematic review of the world literature. J Can Res Ther [serial online] 2021 [cited 2022 Jan 19 ];17:1307-1313
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2021;volume=17;issue=6;spage=1307;epage=1313;aulast=Mishra;type=0