Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 12  |  Issue : 8  |  Page : 271--273

Effect of dezocine combined with propofol on painless gastroscopy in patients with suspect gastric carcinoma


Ji Ma1, Peng Zhang2, Yixuan Zhang2, Zong Chen2, Wenqi Xin2, Donghang Zhang1, Chuangeng Ma2 
1 Department of Endoscopy, Huaihe Hospital Henan University, Kaifeng Henan Province, Kaifeng 475000, PR China
2 Department of Anesthesiology, Huaihe Hospital Henan University, Kaifeng Henan Province, Kaifeng 475000, PR China

Correspondence Address:
Donghang Zhang
Department of Endoscopy, Huaihe Hospital, Henan University, Kaifeng 475000
PR China

Objective: To evaluate the effect of dezocine combined with propofol on painless gastroscopy in patients with suspect gastric carcinoma. Methods: Forty-three patients with gastric carcinoma who have underwent painless gastroscopy were retrospectively analyzed. For the 43 patients, 21 patients received propofol 1 mg/kg for painless gastroscopy (control group) and other 22 cases received dezocine 20 µg/kg plus propofol 1 mg/kg for painless gastroscopy (experiment group). The vital indexes (heart rate [HR], respiratory rate [RR], mean arterial pressure [MAP], and SpO2%), side effects, and recovery time were recorded at the time point T1 (before dosing), T2 (disappearance of eyelash reflex), and T3 (recovery of orientation). Results: The HR, RR, and MAP were significantly decreased in T2 compared to T1 in both experiment and control group (P < 0.05). However, the SpO2% was not changed at T1, T2, and T3 in both experiment and control groups (P > 0.05). The RR at T2 was 16.8 ± 2.1 (n/ min) and 14.2 ± 1.8 (n/min) for experiment and control groups, respectively, with statistical difference (P < 0.05). The incidence rate of respiratory depression and body movement was 0.0%, 27.3% for experiment and 23.8%, 47.6% for control group with statistical difference (P < 0.05). The recovery time was 3.6 ± 0.8 min and 1.8 ± 0.6 min for control and experiment group, respectively, which demonstrated experiment group is much shorter than that of control group with statistical difference (P < 0.05). However, nausea and vomiting rate was not statistically different between the experiment and control groups (P > 0.05). Conclusion: Dezocine combined with propofol on painless gastroscopy can reduce the respiratory depression and body movement without interference of hemodynamics.


How to cite this article:
Ma J, Zhang P, Zhang Y, Chen Z, Xin W, Zhang D, Ma C. Effect of dezocine combined with propofol on painless gastroscopy in patients with suspect gastric carcinoma.J Can Res Ther 2016;12:271-273


How to cite this URL:
Ma J, Zhang P, Zhang Y, Chen Z, Xin W, Zhang D, Ma C. Effect of dezocine combined with propofol on painless gastroscopy in patients with suspect gastric carcinoma. J Can Res Ther [serial online] 2016 [cited 2022 Jul 2 ];12:271-273
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2016;volume=12;issue=8;spage=271;epage=273;aulast=Ma;type=0