Journal of Cancer Research and Therapeutics

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 12  |  Issue : 8  |  Page : 244--247

A meta-analysis of elemene versus DDP intrapleural injection in the treatment of malignant pleural effusion caused by lung cancer


Xiaolong Wang1, Haojie Wang1, Li Li2 
1 Department of Thoracic Surgery, Huaihe Hospital of Henan University, Kaifeng, PR China
2 Nursing College of Henan University, Kaifeng, PR China

Correspondence Address:
Li Li
Nursing College of Henan University, Kaifeng, 475000
PR China

Objective: The objective of this study was to evaluate the clinical efficacy of elemene versus DDP intrapleural injection in the treatment of malignant pleural effusion caused by lung cancer by meta-analysis. Materials and Methods: PubMed (1960 ~ 2016.4), EMBASE (1980 ~ 2016.4), and CNKI (1979 ~ 2016.4) databases were searched to identify the clinical studies of elemene intrapleural injection in the treatment of lung cancer malignant pleural effusion. The odds ratio (OR) was used to evaluate the clinical efficacy of elemene in the treatment of pleural effusion compared to cisplatin (DDP). Results: Seven hundred and Thirty-two subjects with 14 studies were finally included in this meta-analysis. Meta-analysis demonstrated that the objective response rate in elemene group was much higher than that in DDP group (OR = 1.34, 95% confidence interval: 1.07 ~ 1.69, P < 0.05). The Begg's funnel plot and Egger's line regression test showed no statistical publication bias. Conclusion: High clinical efficacy of elemene in the treatment of lung cancer malignant pleural effusion was found compared to DDP.


How to cite this article:
Wang X, Wang H, Li L. A meta-analysis of elemene versus DDP intrapleural injection in the treatment of malignant pleural effusion caused by lung cancer.J Can Res Ther 2016;12:244-247


How to cite this URL:
Wang X, Wang H, Li L. A meta-analysis of elemene versus DDP intrapleural injection in the treatment of malignant pleural effusion caused by lung cancer. J Can Res Ther [serial online] 2016 [cited 2022 Jun 28 ];12:244-247
Available from: https://www.cancerjournal.net/article.asp?issn=0973-1482;year=2016;volume=12;issue=8;spage=244;epage=247;aulast=Wang;type=0