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The lytic skeletal lesions: A rare presentation of carcinoma prostate on 18F-fluorodeoxyglucose positron emission tomography/computed tomography

1 Department of Nuclear Medicine and Molecular Imaging, All India Institutes of Medical Sciences, Nagpur, Maharashtra, India
2 Department of Nuclear Medicine, Tata Memorial Hospital, Dr. E Borges Marg, Parel East, Mumbai, Maharashtra, India
3 Department of Pathology, Homi Bhabha Cancer Hospital and Mahamana Pandit Madanmohan Malaviya Cancer Centre, Sundar Bagiya, BHU Campus, Varanasi, Uttar Pradesh, India

Correspondence Address:
Shantanu Pande,
Department of Nuclear Medicine and Molecular Imaging, All India Institutes of Medical Sciences, Nagpur - 441 108, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcrt.jcrt_1073_22

We describe the 18F-fluorodeoxyglucose positron emission tomography/contrast enhanced computed tomography (FDG PET/CECT) images of a 63-year-old male who complained of back pain and was suspected of multiple myeloma based on magnetic resonance imaging. PET/CECT suggested the FDG avid lesion involving prostate, accompanied by multiple lytic skeletal lesions with no evidence to suggest other possible primary site. A bone marrow biopsy suggested a metastatic adenocarcinoma of primary prostatic origin. Post anti-androgen therapy follow-up FDG PET/CT revealed reductions in the metabolic activities and soft tissue components of most of the metastatic skeletal lesions. These images highlight the possible indication of FDG PET/CT in evaluation of prostatic malignancy in era of 68Ga-PSMA.

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