Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Ahead of Print

Infiltrating duct cell carcinoma in lactating adenoma: A rare case in pair

1 Department of Pathology, Shri Lal Bahadur Shastri Government Medical College, Himachal Pradesh, Mandi, India
2 Department of Surgery, Shri Lal Bahadur Shastri Government Medical College, Mandi, Himachal Pradesh, India
3 Department of Pathology, Dr R.K.G.M.C, Hamirpur, Himachal Pradesh, India
4 Department of Pharmacology, Dr R.K.G.M.C, Hamirpur, Himachal Pradesh, India

Correspondence Address:
Kavita Kumari,
Department of Pathology, Dr R.K.G.M.C. Hamirpur, Himachal Pradesh
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcrt.jcrt_1183_21

Lactating adenomas, though considered being benign, sometimes turn out to be malignant. We are hereby presenting two cases of lactating adenomas which turned out to be harboring infiltrating duct cell carcinoma (DCC). Two lactating women with mass in the breast were referred from surgery for fine-needle aspiration cytology and biopsy. On histopathology, it was found that both had infiltrating DCC (either as collision tumor or as a malignant transformation of lactating adenoma). These cases point toward some association between lactating adenoma and DCC, however, small it may be. Therefore, any mass lesion in the breast should be followed up under strict vigilance for an early diagnosis and management of this deadly disease. A large sample size and elaborate study are required to frame its prognostic relevance. Like estrogen receptor and progesterone receptor, prolactin and prolactin receptor expression can be exploited for developing newer receptor-targeted therapy.

Print this article
  Search Pubmed for
    -  Sharma R
    -  Rattan A
    -  Kumari K
    -  Sharad S
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded6    

Recommend this journal