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Challenges and developments of magnetic resonance image-guided radiation therapy for brain tumors


1 Department of Radiation Oncology, Yashoda Hospitals, Yashoda Cancer Institute, Hyderabad, Telangana; School of Advanced Sciences, Vellore Institute of Technology, Vellore, Tamil Nadu, India
2 School of Advanced Sciences, Vellore Institute of Technology, Vellore, Tamil Nadu, India

Correspondence Address:
Anu Radha Chandrasekaran,
School of Advanced Sciences, Vellore Institute of Technology, Vellore, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jcrt.JCRT_1023_20

Treatment of brain lesions with magnetic resonance imaging (MRI) is indispensable. Although computed tomography (CT) is the gold standard for radiotherapy (RT) planning, recent developments in image-guided RT have compelling reasons to remove CT from the regular RT workflow. Thus, magnetic resonance (MR) only RT is gaining interest rapidly. In this review, we look at how MRI has gained the importance in radiation planning at various stages and why we try to refrain CT imaging. We have elaborated the MR simulation techniques for the brain from different expertise to get a clear insight about the imaging protocols and quality assurance steps tweaked for RT requirements. We have described the basic and complex algorithms utilized to promulgate a CT-like data set from appropriate MR sequences for crucial treatment planning process. In a small section, we have narrated the significance of dose escalation using the functional MR images. In the final section, we describe a pivotal (yet least researched) area of digital radiograph generation using MR dataset for day-to-day pretreatment image verification on couch.


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    -  Chandrasekaran AR
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