ORIGINAL ARTICLE |
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Ahead of Print |
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A comparison of radiotherapy treatment planning techniques in patients with rectal cancers by analyzing testes doses
Evrim Duman1, Yılmaz Bilek1, Gokay Ceyran2
1 Department of Radiation Oncology, University of Health Sciences Antalya Education and Research Hospital, Antalya, Turkey 2 Department of Radiation Oncology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey
Correspondence Address:
Evrim Duman, Department of Radiation Oncology, University of Health Sciences Antalya Education and Research Hospital, Antalya Turkey
 Source of Support: None, Conflict of Interest: None DOI: 10.4103/jcrt.JCRT_328_19
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Purpose: To evaluate the target volume (TV) and critical organ doses with priority of testes with the comparison of conformal radiotherapy (CRT), dynamic intensity-modulated radiotherapy (DIMRT), and volumetric modulated arc therapy (VMAT) techniques.
Materials and Methods: CRT, DIMRT, and VMAT techniques were generated on computed tomography images in prone position of 10 male patients with distal rectal cancer. Conformity index (CI), heterogeneity index (HI), treatment time, and monitor units were examined; dose-volume-histograms (DVHs) for the TV and the organs at risk (OARs) were evaluated.
Results: Target dose coverage of all treatment plans was similar. HI and CI values for DIMRT and VMAT were closer to “1” compared to CRT. DVH parameters for OARs were decreased with DIMRT and VMAT compared to CRT. The percent volume (Vx) of 3 Gy dose of testes was 62.01% (±25.45%), 42.68% (±16.42%), and 35.89% (±14.97%) in the CRT, DIMRT, and VMAT techniques, respectively. V3 of testes decreased with VMAT compared to CRT and DIMRT (P = 0.008 and P = 0.051, respectively).
Conclusion: Modern radiotherapy techniques are superior to conformal techniques in planning quality parameters and sparing OARs. DIMRT and VMAT could be considered instead of CRT in the desire to preserve fertility of patients with rectal cancer.
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