Risk of pneumothorax caused by computerized tomography-guided percutaneous core needle biopsy of the lung in elderly and young patients
Wei Zhou1, Xuejuan Yu1, Yang Song2, Fengxia Yang3, Chunhai Li4, Bo Liu4, Haipeng Jia4, Dexiang Wang5
1 Department of Radiation Oncology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, China
2 Department of Oncology, Liaocheng Tumor Hospital, Liaocheng, Shandong, China
3 Shandong Medicinal Biotechnology Center, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
4 Department of Radiology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, China
5 Department of Pulmonary and Critical Care Medicine, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, China
Department of Pulmonary and Critical Care Medicine, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 Wenhuaxi Street, Jinan, Shandong Province, 250012
Source of Support: None, Conflict of Interest: None
Context: The incidences and risk factors caused by computed tomography (CT)-guided percutaneous computed tomography-guided needle biopsies (PCNBs) in elderly and young patients were not very clear.
Aims: This study explored the different incidences of pneumothorax caused by PCNBs and related risk factors in elderly and young patients.
Settings and Design: The medical records of 1100 patients who underwent CT-guided PCNBs in a hospital from January 2018 to December 2019 were retrospectively reviewed.
Subjects and Methods: Data relating to the patients, lesions, techniques, and diagnoses were collected according to the ethical standards of the institutional research committee (registration number: KYLL-202008-145).
Statistical Analysis Used: The variables were significant by univariate analysis and further analyzed by multivariate logistic regression analysis.
Results: In the 1100 patients with PCNBs, the incidence of pneumothorax in groups ≥65 years old and <65 years old was 15.2% and 12.9%, respectively. There was no significant difference in the incidence of pneumothorax between the young and elderly patients. In elderly and young patients, emphysema along the needle path and dwell time was independent predictors. However, in young patients, lesion-abutting pleura was an independent risk factor for pneumothorax, but not in elderly patients.
Conclusions: The risk of pneumothorax caused by CT-guided percutaneous core needle biopsy of the lung does not increase in elderly patients. Emphysema along the needle path and dwell time is independent predictors of pneumothorax in elderly and young patients.