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Year : 2014  |  Volume : 10  |  Issue : 7  |  Page : 229-231

Evaluation of computed tomography-guided parapharyngeal mass needle biopsy through mandibular notch for diagnosis of recurrent nasopharygeal carcinoma

1 Department of Radiology, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, China
2 Department of Oncology, Zhejiang Hospital, Hangzhou, Zhejiang 310013, China

Correspondence Address:
Hao Jiang
Department of Oncology, Zhejiang Hospital, Hangzhou, Zhejiang 310013
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.145887

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Objective: The aim was to evaluate the effectiveness of computed tomography (CT)-guided fine-needle aspiration biopsy (FNAB) from Mandibular notch and under the zygomatic arch for pathological diagnosis of recurrence nasopharyngeal carcinoma (NPC) after radiotherapy (RT). Materials and Methods: Between October 2007 and December 2013, 48 patients with suspected recurrent NPC underwent CT-guided FNAB. A modified coaxial technique was used in all cases, and multiple samples were obtained for histological studies. Results: We obtained a definite histological diagnosis with 87.5% (42/48) overall diagnostic accuracy. In 42 patients the needle aspirate confirmed a clinical suspicion of recurrent disease and the histologic finding was positive (10 cases of squamous cell carcinoma, 3 cases of adenocarcinoma, finding tumor cells tend to squamous cell carcinoma in 24 patients and undifferentiated carcinoma in 5 patients). In the six cases of "no tumor seen" confirmation was made by clinical and imaging follow-up showing 2 tumor relapse and 4 fibrillation. Conclusion: CT-guided FNAB from Mandibular notch and under the zygomatic arch is a safe and accurate technique useful for pathological diagnosis of recurrence NPC after RT.

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