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Year : 2012  |  Volume : 8  |  Issue : 2  |  Page : 317-319

Inflammatory myofibroblastic tumor appendix with concomitant mucosal dysplasia, simulating pseudomyxoma on preoperative aspiration cytology

1 Department of Pathology, G B Pant Hospital, Jawaharlal Nehru Marg, New Delhi, India
2 Department of Pathology, Bhopal Memorial Hospital and Research centre, Bhopal, India
3 Department of Pathology, Institute of Liver and Biliary Sciences, Vasant Kunj, New Delhi, India
4 Department of Gastrointestinal Surgery, G B Pant Hospital, Jawaharlal Nehru Marg, New Delhi, India

Correspondence Address:
Puja Sakhuja
Department of Pathology, Academic Block, G B Pant Hospital, Jawaharlal Nehru Marg, New Delhi -110002
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1482.99004

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Inflammatory myofibroblastic tumor (IMT) has been described as a pseudosarcomatous proliferation of spindled myofibroblasts admixed with lymphoplasmacytic cells. The various terminologies like inflammatory pseudotumor, plasma cell granuloma, and inflammatory myofibrohistiocytic proliferation, used to describe this entity, highlight the controversial etiopathogenesis of this relatively indolent neoplasm. IMT has now been described in different anatomic locations. However, cases occurring in the gastrointestinal tract are rare with very few cases described in the appendix. We present a case of inflammatory myofibroblastic tumor appendix with mucosal dysplasia in a 41-year-old male, presenting with abdominal pain and lump in the right iliac fossa. Aspiration cytology yielded few atypical epithelial cells and spindle cells in a mucinous background, suggesting the possibility of pseudomyxoma peritonei. Awareness of IMT appendix with rare presence of mucosal dysplasia may help in preventing overzealous resection, especially in situations that on preoperative evaluation may suggest malignancy.

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