Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
 
CORRESPONDENCE
Ahead of Print

Multiple subcutaneous metastases as the solitary presenting site of colorectal cancer


 Department of Radiotherapy, Regional Institute of Medical Sciences, Imphal, Manipur, India

Correspondence Address:
Chandran Nallathambi,
Department of Radiotherapy, Regional Institute of Medical Sciences, Lamphelpat, Imphal 795 004, Manipur
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Skin metastases, as a presenting symptom of gastrointestinal malignancies, are very rare and signify aggressive disease. They usually occur after a long period of diagnosis and along with other visceral metastases. We present the case of an 18-year-old male with diffuse subcutaneous metastases as a presenting feature and as the only site of distant metastases due to rectosigmoid adenocarcinoma. They clinically mimic benign skin lesions and the patient might not present to an oncologist. The diagnosis has to be established by skin biopsy, which will show tumor cell infiltration of the epidermis, dermis, and/or subcutaneous fat. There is no established local treatment for diffuse lesions. Systemic chemotherapy indicated for metastatic colon carcinoma was employed with not much favorable response. Irinotecan based chemotherapy also resulted in posterior reversible encephalopathy syndrome in this patient. Overall, the disease carries a poor prognosis and with no effective treatment available the survival is less than a year.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Nallathambi C
    -  Singh IY
    -  Patton Z
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed268    
    PDF Downloaded22    

Recommend this journal